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Artificial sweeteners. Looks like sugar, tastes like sugar (only sweeter), yet no calories. You can even bake with some artificial sweeteners! Seriously, what could be better? If it sounds too good to be true, it probably is. Read on to find out more about benefits and consequences of the sweet stuff.
The first artificial sweetener was accidentally discovered in 1879 but it wasn’t until the 1980’s and 90’s that they were recognized as a possible solution to the obesity epidemic. The FDA has approved acesulfame-potassium, aspartame, saccharin, and sucralose for use in the United States. Saccharin was discovered in 1879 and has weathered a lot of controversy. It is known by the trade name, Sweet-N-Low (pink packet). Aspartame was approved in 1981 and is marketed as Equal (blue packet). Sucralose was approved in 1998 and is sold as Splenda (yellow packets). Acesulfame-potassium is often added to both Aspartame and Sucralose in order to mask the bitter taste. All sweeteners are marketed as being a healthy alternative for those looking to indulge their sweet tooth without any calorie consequences. Because of their zero-calorie status, artificial sweeteners have become a major focus in the health industry due to their ability to sweeten beverages and food products without added calories. While it is true that artificial sweeteners provide the sweet taste we crave for negligible calories, there is intense discussion in the scientific community as to the consequences of regular consumption. The Food and Drug Administration (FDA) has deemed artificial sweeteners to be safe, yet epidemiological and observational evidence points to a link between artificial sweeteners and weight gain, citing a variety of possible pathways.
There are a lot of things we don't know about artificial sweeteners and how they affect the human body, but here are some of the consequences based on available research.
On a cellular level, artificial sweeteners alter metabolic processes in dramatic ways. However, when we zoom out and study weight gain in humans, both healthy and obese as it relates the artificial sweeteners, the results are less clear. First of all, the human body is an amazing creation, adaptable and resilient to the constant onslaught of unhealthy behaviors and foods we sling at it. Humans can abuse their bodies for many years before the consequences start to set in. Second, it is difficult to assess long term effects of sweeteners on humans because most studies are limited in duration. Third, the effects of artificial sweeteners are more pronounced in people who are already overweight or obese or with glucose impairment as opposed to healthy individuals. Intermittent use of sweeteners in a healthy weight person will have less consequences than use in an obese person because the obese person is already metabolically impaired. Finally, although we lump artificial sweeteners together as one, they are all different. Each one has a unique chemical structure and is treated differently by the body so while sucralose may show certain effects on the body, aspartame may show others.
What about Stevia? Stevia is not considered an artificial sweetener because it is sourced from a plant. And while Stevia may have some side effects such as dizziness, numbness, nausea and bloating, there are relatively few studies on how it might affect the gut microbiome, glucose homeostasis or taste receptors. So the short answer is, we just don't know yet.
The safety and benefit of using artificial sweeteners is a controversial topic and plenty of people say they are just fine, including the FDA. Artificial sweeteners are also backed by some billion dollar companies, including Coca-Cola and Pepsi-Co. There are also plenty of studies out there that find "no significant difference" when it comes to weight gain in humans. As a consumer, it can be very difficult to make informed choices when you are given a deluge of conflicting evidence to base your decision off of. However, given all the possible effects, I think I’ll stick to water.
Exercise is man's best medicine
--Hippocrates
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